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Wednesday, August 5, 2015

Synthetic Hormones In The Food (rGBH) - Myopia Link

On wikipedia at Myopia
A number of studies have shown that myopic individuals attain a higher level of education on average,[5][6][7] and many studies[8] have shown a correlation between myopia and a higher intelligence quotient (IQ).

From wikipedia:
United States[edit]

Myopia is common in the United States, with research suggesting this condition has increased dramatically in recent decades. In 1971–1972, the National Health and Nutrition Examination Survey provided the earliest nationally representative estimates for myopia prevalence in the U.S., and found the prevalence in persons aged 12–54 was 25.0%. Using the same method, in 1999–2004, myopia prevalence was estimated to have climbed to 41.6%.[88]
Myopia - Wikipedia, the free encyclopedia


A 2012 review of animal and human epidemiological studies of heredity and environmental factors could not find strong evidence for any cause, although many theories have been discredited.[3] Because twins and relatives are more likely to get myopia under similar circumstances, there must be a hereditary factor, but because myopia has been increasing so rapidly throughout the developed world, environmental factors must be more important.;[4]

Cows are injected with a hormone called rGBH = recombinant bovine growth hormone
with the purpose to produce more milk

Wikipedia says:

During this process „the effects are mediated by the insulin-like growth factor (IGF) system, which is upregulated in response to BST or rBST administration in well-fed cows.

Now let’s see what about IGF:

The insulin-like growth factors (IGFs) are proteins with high sequence similarityto insulin. 

Insulin-like growth factor 1
From Wikipedia, the free encyclopedia
Insulin-like growth factor 1 (IGF-1), is a protein that in humans is encoded by the IGF1 gene.[1][2] 
Its effects were termed "nonsuppressible insulin-like activity" (NSILA) in the 1970s.
IGF-1 is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults.
A synthetic analog of IGF-1, mecasermin, is used for the treatment of growth failure.
Back to anabolic from wikipedia:
The classic anabolic hormones are the anabolic steroids
Also from wikipedia:

Biological significance[edit]

Steroids and their metabolites often function as signalling molecules. The most notable examples are the steroid hormones.
Now we find this article:
Acute Pancreatitis Associated with Growth Hormone Therapy for Short Stature
N Engl J Med 1995; 332:401-402February 9, 1995DOI: 10.1056/NEJM199502093320618
Insulin acts as a powerful stimulator of axial myopia in chicks.
Needless to remind that IGF is also carcinogenic: 


The American Cancer Society has reviewed the evidence concerning IGF-1 in milk from rBST treated cows, and found that: "While there may be a link between IGF-1 blood levels and cancer, the exact nature of this link remains unclear. 
Report on the Food and Drug Administration's Review of the Safety of Recombinant Bovine Somatotropin
This report was updated on April 23, 2009 to clarify quantities of growth hormone found in milk and those used in the 1989 rat study.
SEARCH FOR „APPEAR”! The expression "appears to..." is in the text 5 times, which proves that they have no idea if rGBH is toxic or not.  
Nature Medicine 5, 1390 - 1395 (1999) 
doi :10.1038/70963

Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor

Lois E. H. Smith1, Wei Shen1, Carole Perruzzi2, Shay Soker3, Fumi Kinose1, Xianghong Xu1, Gregory Robinson1, Sam Driver1, Joyce Bischoff3, Bei Zhang4, James M. Schaeffer4 & Donald R. Senger2


Although insulin-like growth factor 1 (IGF-1) has been associated with retinopathy, proof of a direct relationship has been lacking. Here we show that an IGF-1 receptor antagonist suppresses retinal neovascularization in vivo, and infer that interactions between IGF-1 and the IGF-1 receptor are necessary for induction of maximal neovascularization by vascular endothelial growth factor (VEGF). IGF-1 receptor regulation of VEGF action is mediated at least in part through control of VEGF activation of p44/42 mitogen-activated protein kinase, establishing a hierarchical relationship between IGF-1 and VEGF receptors. These findings establish an essential role for IGF-1 in angiogenesis and demonstrate a new target for control of retinopathy. They also explain why diabetic retinopathy initially increases with the onset of insulin treatment. IGF-1 levels, low in untreated diabetes, rise with insulin therapy, permitting VEGF-induced retinopathy.



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