Mask Hypoxia in Subjects Using Masks to Prevent Infection Spread
https://clinicaltrials.gov/ct2/show/NCT04670484
Hypoxia (oxygen deprivation) is known to be associated with deep vein thrombosis and venous thromboembolism.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627841/
New link between hypoxia and blood clot risk
https://www.sciencedaily.com/releases/2018/08/180802115657.htm#:~:text=Summary%3A,threatening%20blood%20clots%20(thrombosis).
Ischemic stroke occurs when a blood clot blocks or narrows an artery leading to the brain.
https://www.mayoclinic.org/ischemic-stroke/img-20009031
Study shows a possible connection between stroke-like symptoms and coronavirus
by Talia KirklandFriday, May 8th 2020
https://local21news.com/news/local/studies-show-a-possible-connection-between-stroke-like-symptoms-and-coronavirus
Hypoxic-ischemic encephalopathy, or HIE, is the brain injury caused by oxygen deprivation to the brain, also commonly known as intrapartum asphyxia.
https://www.cerebralpalsy.org/about-cerebral-palsy/cause/hypoxic-ischemic-encephalopathy
Acute hypoxemia may result in hypoxic ischemic encephalopathy.
Prolonged hypoxia also causes BBB disruption leading to leaky capillaries which can produce microhemorrhages.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284232/
Acute hypoxemia (see also Oxygen Desaturation) may cause dyspnea, restlessness, and anxiety. Signs include confusion or alteration of consciousness, cyanosis, tachypnea, tachycardia, and diaphoresis. Cardiac arrhythmia and coma can result.
https://www.msdmanuals.com/professional/critical-care-medicine/respiratory-failure-and-mechanical-ventilation/acute-hypoxemic-respiratory-failure-ahrf,-ards?redirectid=8#:~:text=Acute%20hypoxemia%20(see%20also%20Oxygen,arrhythmia%20and%20coma%20can%20result.
DECEASED COVID-19 PATIENTS SHOW HYPOXIC INJURY IN THE BRAIN
“Our findings showed high levels of hypoxic-ischemic injury, which is to be expected in patients with severe lung disease,” says Isaac Solomon, MD, PhD, a pathologist in the Brigham’s Department of Pathology.
Autopsies Show Hypoxia, Not Encephalitis
When the brain is deprived of oxygen for an extended period of time, neurons begin to die, which tends to be most evident in the hippocampus, cerebellum and cerebral cortex. Pathologists observed neuronal death in these brain areas of all 18 patients. But there wasn’t any evidence of encephalitis, or acute inflammation in the brain, which is typically seen in arboviruses, human immunodeficiency virus (HIV), and herpes simplex virus (HSV-1).
“We didn’t see any histological evidence of the virus,” says Dr. Solomon. “With viral encephalitis, we typically see a plethora of lymphocytes and microglia, which destroy virus-infected neurons, but we didn’t see anything like that.”
https://www.brighamhealthonamission.org/2020/07/29/deceased-covid-19-patients-show-hypoxic-injury-in-the-brain/
Preliminary report on surgical mask induced deoxygenation during major surgery
https://scielo.isciii.es/pdf/neuro/v19n2/3.pdf
